Hs3st6^em2Vnp
Endonuclease-mediated Allele Detail

Summary

• Symbol: Hs3st6^em2Vnp
• Name: heparan sulfate (glucosamine) 3-O-sulfotransferase 6; endonuclease-mediated mutation 2, Vaishali N Patel
• MGI ID: MGI:8235789
• Gene: Hs3st6 Location: Chr17:24971962-24977658 bp, + strand Genetic Position: Chr17, 12.53 cM
• Alliance: Hs3st6^em2Vnp page

Mutation origin

• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR-targeting exon 1 deleted 38 bp. (J:360826)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Hs3st6 Mutation: 14 strains or lines available

References

• Original: J:360826 Patel VN, et al., Loss of 3-O-sulfotransferase enzymes, Hs3st3a1 and Hs3st3b1, reduces kidney and glomerular size and disrupts glomerular architecture. Matrix Biol. 2024 Nov;133:134-149
• All: 1 reference(s)