Ccdc178^em1Wli
Endonuclease-mediated Allele Detail

Summary

• Symbol: Ccdc178^em1Wli
• Name: coiled coil domain containing 178; endonuclease-mediated mutation 1, Wei Li
• MGI ID: MGI:8216644
• Gene: Ccdc178 Location: Chr18:21943954-22304453 bp, - strand Genetic Position: Chr18, 11.96 cM, cytoband A2
• Alliance: Ccdc178^em1Wli page

Mutation origin

• Strain of Origin: Not Applicable

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR/Cas9 technology generated a 5715 bp deletion encompassing exons 6 and 7. (J:367061)

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ccdc178 Mutation: 58 strains or lines available

References

• Original: J:367061 Dong F, et al., CCDC178-mediated cytoskeleton assembly is required for spermiogenesis in mice. Genes Dis. 2024 Nov;11(6):101132
• All: 1 reference(s)