Gpr45^em1Zz
Endonuclease-mediated Allele Detail

Summary

• Symbol: Gpr45^em1Zz
• Name: G protein-coupled receptor 45; endonuclease-mediated mutation 1, Zhao Zhang
• MGI ID: MGI:8215534
• Gene: Gpr45 Location: Chr1:42992032-43074611 bp, + strand Genetic Position: Chr1, 21.88 cM, cytoband C1
• Alliance: Gpr45^em1Zz page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Not Specified
• CRISPR/Cas9 technology generated a knock-out allele. (J:367505)

Expression

In Structures Affected by this Mutation:

6 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gpr45 Mutation: 25 strains or lines available

References

• Original: J:367505 Xun Y, et al., GPR45 modulates Galpha(s) at primary cilia of the paraventricular hypothalamus to control food intake. Science. 2025 Jun 5;388(6751):eadp3989
• All: 1 reference(s)