Mtfr1l^em2Gpt
Endonuclease-mediated Allele Detail

Summary

• Symbol: Mtfr1l^em2Gpt
• Name: mitochondrial fission regulator 1-like; endonuclease-mediated mutation 2, GemPharmatech
• MGI ID: MGI:8171739
• Synonyms: Mtfr1l^-, Mtfr1l^em1Cd
• Gene: Mtfr1l Location: Chr4:134252866-134262698 bp, - strand Genetic Position: Chr4, 66.83 cM
• Alliance: Mtfr1l^em2Gpt page

Mutation origin

• Strain of Origin: C57BL/6JGpt

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details:

  CRISPR-targeting removed sequence from the coding region. Exons 4 to 6 were deleted. Western blot analysis confirmed the absence of protein expression in the heart, brain and retina of 2-month-old homozygous mutant mice. (J:293217, J:390197)

Expression

In Structures Affected by this Mutation:

4 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Mtfr1l Mutation: 15 strains or lines available

References

• Original: J:293217 GemPharmatech, GemPharmatech Website. 2020
• All: 2 reference(s)