Rag2^{em1(rtTA)Rygo}
Endonuclease-mediated Allele Detail

Summary

• Symbol: Rag2^{em1(rtTA)Rygo}
• Name: recombination activating gene 2; endonuclease-mediated mutation 1, Ryo Goitsuka
• MGI ID: MGI:8164218
• Synonyms: RAG2-rtTA
• Gene: Rag2 Location: Chr2:101455063-101462874 bp, + strand Genetic Position: Chr2, 53.87 cM
• Alliance: Rag2^{em1(rtTA)Rygo} page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Transactivator)
• Mutation: Insertion
• CRISPR-targeting introduced the reverse tetracycline transactivator. (J:363765)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Rag2 Mutation: 121 strains or lines available

References

• Original: J:363765 Fujisaki K, et al., B Cells of Early-life Origin Defined by RAG2-based Lymphoid Cell Tracking under Native Hematopoietic Conditions. J Immunol. 2024 Aug 1;213(3):296-305
• All: 1 reference(s)