Rnf145^em1Pton
Endonuclease-mediated Allele Detail

Summary

• Symbol: Rnf145^em1Pton
• Name: ring finger protein 145; endonuclease-mediated mutation 1, Peter Tontonoz
• MGI ID: MGI:8162185
• Synonyms: Rnf145^-
• Gene: Rnf145 Location: Chr11:44409791-44456347 bp, + strand Genetic Position: Chr11, 25.94 cM, cytoband B1.1
• Alliance: Rnf145^em1Pton page

Mutation origin

• Strain of Origin: Not Specified

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Exon 1 was targeted by CRISPR/Cas9 genome editing technology. (J:249975)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Rnf145 Mutation: 50 strains or lines available

References

• Original: J:249975 Zhang L, et al., Inhibition of cholesterol biosynthesis through RNF145-dependent ubiquitination of SCAP. Elife. 2017 Oct 25;6:e28766
• All: 1 reference(s)