Mtrex^tm1.1Hyfn
Targeted Allele Detail

Summary

• Symbol: Mtrex^tm1.1Hyfn
• Name: Mtr4 exosome RNA helicase; targeted mutation 1.1, Heng-Yu Fan
• MGI ID: MGI:8161057
• Synonyms: Mtr4^fl
• Gene: Mtrex Location: Chr13:113004306-113063914 bp, - strand Genetic Position: Chr13, 63.93 cM, cytoband D2.2
• Alliance: Mtrex^tm1.1Hyfn page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:360942
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: LoxP sites were inserted to flank exon 6, and an adjacent frt-flanked neomycin selection cassette was removed via FLP-mediated recombination. (J:360942)

Expression

In Mice Carrying this Mutation:	1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Mtrex Mutation: 54 strains or lines available

References

• Original: J:360942 Wu YW, et al., RNA surveillance by the RNA helicase MTR4 determines volume of mouse oocytes. Dev Cell. 2024 Oct 4
• All: 1 reference(s)