Ppm1d^{em1.1(IMPC)Wtsi}
Endonuclease-mediated Allele Detail

Summary

• Symbol: Ppm1d^{em1.1(IMPC)Wtsi}
• Name: protein phosphatase 1D magnesium-dependent, delta isoform; endonuclease-mediated mutation 1.1, Wellcome Trust Sanger Institute
• MGI ID: MGI:7861436
• Synonyms: Ppm1d^{tm1.2(IMPC)Wtsi}
• Gene: Ppm1d Location: Chr11:85202080-85237897 bp, + strand Genetic Position: Chr11, 51.34 cM
• Alliance: Ppm1d^{em1.1(IMPC)Wtsi} page
• IMPC: Ppm1d gene page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:82809
• Parent Cell Line: JM8A1.N3 (ES Cell)
• Strain of Origin: C57BL/6N-A^tm1Brd
• Project Collection: IMPC

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The targeting vector replaced exon 6 with a human codon optimized exon 6 followed by a stop cassette and human codon optimized point mutated exon 6 resulting in deletion of T Chr 11:85345824 cause a premature stop codon at L476stop. Post flp deletion of selectable marker. (J:82809)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Ppm1d Mutation: 33 strains or lines available

References

• Original: J:82809 European Mouse Mutant Archive, Information obtained from the European Mouse Mutant Archive (EMMA). Unpublished. 2003-2013
• All: 1 reference(s)