Spag7^em1Zwu
Endonuclease-mediated Allele Detail

Summary

• Symbol: Spag7^em1Zwu
• Name: sperm associated antigen 7; endonuclease-mediated mutation 1, Zhidan Wu
• MGI ID: MGI:7779594
• Synonyms: Spag7^fl
• Gene: Spag7 Location: Chr11:70554597-70560242 bp, - strand Genetic Position: Chr11, 43.21 cM
• Alliance: Spag7^em1Zwu page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready)
• Mutation: Insertion
• Exon 2 was flanked by loxP sites via CRISPR/Cas9 technology. (J:357463)

Expression

In Mice Carrying this Mutation:

15 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Spag7 Mutation: 45 strains or lines available

References

• Original: J:357463 Flaherty SE 3rd, et al., SPAG7 deletion causes intrauterine growth restriction, resulting in adulthood obesity and metabolic dysfunction. Elife. 2024 Jul 26;12
• All: 1 reference(s)