Fcgr1^{tm1(FCGR1A)Cya}
Targeted Allele Detail

Summary

• Symbol: Fcgr1^{tm1(FCGR1A)Cya}
• Name: Fc receptor, IgG, high affinity I; targeted mutation 1, Cyagen Biosciences
• MGI ID: MGI:7657247
• Synonyms: Fcgr1^{tm1(hFCGR1A)Cya}
• Gene: Fcgr1 Location: Chr3:96190225-96201285 bp, - strand Genetic Position: Chr3, 41.72 cM
• Alliance: Fcgr1^{tm1(FCGR1A)Cya} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:326541
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6N

Mutation description

• Allele Type: Targeted (Inserted expressed sequence, Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Fcgr1^{tm1(FCGR1A)Cya} expresses 1 gene
  Knock-in expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  FCGR1A (2209)

  Fcgr1

  (MGI:95498)

• Mutation details: The mouse Fcgr1 gene sequence (from about 5kb upstream of the Fcgr1 gene to about 3kb downstream of the Fcgr1 gene) was completely replaced with the corresponding sequence in the human FCGR1A gene (from about 7kb upstream of the FCGR1A gene to about 3kb downstream of the FCGR1A gene) by gene editing technology. (J:326541)
• Inheritance: Not Specified

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Fcgr1 Mutation: 34 strains or lines available

References

• Original: J:326541 Cyagen Biosciences Inc., Cyagen Biosciences Website. 2022
• All: 1 reference(s)