Hoxd^{tm18.1(Hoxd11)Ddu}
Targeted Allele Detail

Summary

• Symbol: Hoxd^{tm18.1(Hoxd11)Ddu}
• Name: homeobox D cluster; targeted mutation 18.1, Denis Duboule
• MGI ID: MGI:7639875
• Synonyms: Hoxd11/lacZ/loxP
• Gene: Hoxd Location: unknown Genetic Position: Chr2, Syntenic

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:70547
• Parent Cell Line: D3 (ES Cell)
• Strain of Origin: 129S2/SvPas

Mutation description

• Allele Type: Targeted (Inserted expressed sequence, Reporter)
• Mutation: Insertion
• Hoxd^{tm18.1(Hoxd11)Ddu} expresses 1 gene
  Knock-in expresses:
  

  Organism	Expressed Gene	Note
  mouse	Hoxd11 (MGI:96203)

• Mutation details: The targeting construct inserted Hoxd11/lac/loxP reporter gene inserted 5' of Hoxd13. Cre-mediated recombination removed the selection cassette leaving a single loxP site. (J:70547)

Expression

In Mice Carrying this Mutation:

23 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Hoxd Mutation: 0 strains or lines available

References

• Original: J:70547 Zakany J, et al., Localized and transient transcription of Hox genes suggests a link between patterning and the segmentation clock. Cell. 2001 Jul 27;106(2):207-17
• All: 1 reference(s)