Cd28^{em4(CD28)Smoc}
Endonuclease-mediated Allele Detail

Summary

• Symbol: Cd28^{em4(CD28)Smoc}
• Name: CD28 antigen; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
• MGI ID: MGI:7627387
• Gene: Cd28 Location: Chr1:60785547-60812521 bp, + strand Genetic Position: Chr1, 30.52 cM, cytoband C1-C3
• Alliance: Cd28^{em4(CD28)Smoc} page

Mutation origin

• Strain of Origin: BALB/c

Mutation description

• Allele Type: Endonuclease-mediated (Inserted expressed sequence, Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Cd28^{em4(CD28)Smoc} expresses 1 gene
  Knock-in expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  CD28 (940)

  Cd28	(MGI:88327)

• The endogenous mice Ctla4 and Cd28 gene was replaced by human CTLA4 and CD28 gene. (J:238766)
• Inheritance: Not Specified

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cd28 Mutation: 37 strains or lines available

References

• Original: J:238766 Shanghai Model Organisms Center, Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China. MGI Direct Data Submission. 2017
• All: 1 reference(s)