Depp1^em1(IMPC)Mbp
Endonuclease-mediated Allele Detail

Summary

• Symbol: Depp1^em1(IMPC)Mbp
• Name: DEPP1 autophagy regulator; endonuclease-mediated mutation 1, Mouse Biology Program, UC Davis
• MGI ID: MGI:7615153
• Gene: Depp1 Location: Chr6:116627645-116629808 bp, + strand Genetic Position: Chr6, 53.83 cM
• Alliance: Depp1^em1(IMPC)Mbp page
• IMPC: Depp1 gene page

Mutation origin

• Strain of Origin: C57BL/6NCrl
• Project Collection: IMPC

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: This allele was generated at University of California, Davis using Cas9 and guides with spacer sequences CCCGTGTAGCATCTCCGATG and GGATTGTCACCTAGGTACCC that targeted exon(s) ENSMUSE00000457830.7 ENSMUSE00001001922.3. This resulted in deletion(s) of 5 bp (location: Chr6:116628413-116628417; GRCm39), 1451 bp (location: Chr6:116628563-116630013; GRCm39). This description was generated automatically. Additional molecular information including FASTA sequence support for this allele can be found here: (IMPC Gene page) and viewed in a genome context here: (IMPC Genome Browser). (J:384794)

• Inheritance: Not Specified

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Depp1 Mutation: 20 strains or lines available

References

• Original: J:265051 MGI and IMPC, MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC). Database Release. 2018-2023
• All: 2 reference(s)