Zfp503^tm1.1Lif
Targeted Allele Detail

Summary

• Symbol: Zfp503^tm1.1Lif
• Name: zinc finger protein 503; targeted mutation 1.1, Fu-Chin Liu
• MGI ID: MGI:7606867
• Gene: Zfp503 Location: Chr14:22034030-22039669 bp, - strand Genetic Position: Chr14, 12.0 cM
• Alliance: Zfp503^tm1.1Lif page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:286635
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A loxP site was inserted upstream of exon 3 and an FRT-flanked neo cassette and loxP site were inserted downstream of exon 3 via homologous recombination. Recombinase mediated recombination deleted exon 3 and the neo cassette. Immunostaining analysis confirmed the absence of protein expression in striatum from E18.5 homozygous mice. (J:286635)

Expression

In Structures Affected by this Mutation:

4 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Zfp503 Mutation: 36 strains or lines available

References

• Original: J:286635 Chen SY, et al., Parcellation of the striatal complex into dorsal and ventral districts. Proc Natl Acad Sci U S A. 2020 Mar 31;117(13):7418-7429
• All: 2 reference(s)