Dtx3l^em1Cya
Endonuclease-mediated Allele Detail

Summary

• Symbol: Dtx3l^em1Cya
• Name: deltex 3-like, E3 ubiquitin ligase; endonuclease-mediated mutation 1, Cyagen Biosciences
• MGI ID: MGI:7583470
• Synonyms: Dtx3l^em1
• Gene: Dtx3l Location: Chr16:35746885-35759397 bp, - strand Genetic Position: Chr16, 25.43 cM
• Alliance: Dtx3l^em1Cya page

Mutation origin

• Strain of Origin: C57BL/6JCya

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Exon 2~5 will be selected as target site. (J:326541, J:369823)
• Inheritance: Not Specified

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Dtx3l Mutation: 33 strains or lines available

References

• Original: J:369823 Tong L, et al., Viruses hijack FPN1 to disrupt iron withholding and suppress host defense. Nat Commun. 2025 Jul 1;16(1):5912
• All: 2 reference(s)