Gal3st1^em1Jldu
Endonuclease-mediated Allele Detail

Summary

• Symbol: Gal3st1^em1Jldu
• Name: galactose-3-O-sulfotransferase 1; endonuclease-mediated mutation 1, Jeffrey L Dupree
• MGI ID: MGI:7580758
• Synonyms: Cst^fl
• Gene: Gal3st1 Location: Chr11:3933636-3949326 bp, + strand Genetic Position: Chr11, 2.81 cM, cytoband A1
• Alliance: Gal3st1^em1Jldu page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready)
• Mutation: Insertion
• LoxP sites were inserted flanking exons 2 and 3 via CRISPR/Cas9 technology. (J:344973)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gal3st1 Mutation: 20 strains or lines available

References

• Original: J:344973 Dustin E, et al., Adult-onset depletion of sulfatide leads to axonal degeneration with relative myelin sparing. Glia. 2023 Sep;71(9):2285-2303
• All: 6 reference(s)