Htra3^tm1.1Hohj
Targeted Allele Detail

Summary

• Symbol: Htra3^tm1.1Hohj
• Name: HtrA serine peptidase 3; targeted mutation 1.1, Josephine Hoh
• MGI ID: MGI:7579338
• Gene: Htra3 Location: Chr5:35809367-35837126 bp, - strand Genetic Position: Chr5, 18.49 cM, cytoband B1
• Alliance: Htra3^tm1.1Hohj page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:343288
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: The targeting vector is designed to insert a loxP site upstream of exon 3, and an FRT-flanked PGK-neomycin cassette followed by a loxP-site downstream of exon 3. Cre-mediated recombination removed exon 3 and the neo cassette. (J:343288)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Htra3 Mutation: 21 strains or lines available

References

• Original: J:343288 Patterson VL, et al., A Phenotyping Regimen for Genetically Modified Mice Used to Study Genes Implicated in Human Diseases of Aging. J Vis Exp. 2016 Jul 14;(113)
• All: 1 reference(s)