Zeb1^em1Cnbbm
Endonuclease-mediated Allele Detail

Summary

• Symbol: Zeb1^em1Cnbbm
• Name: zinc finger E-box binding homeobox 1; endonuclease-mediated mutation 1, Transgenesis Service CNB-CBMSO
• MGI ID: MGI:7568837
• Synonyms: Zeb1^fl
• Gene: Zeb1 Location: Chr18:5591860-5775467 bp, + strand Genetic Position: Chr18, 4.42 cM
• Alliance: Zeb1^em1Cnbbm page

Mutation origin

• Strain of Origin: (C57BL/6 x CBA)F2

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready)
• Mutation: Insertion
• Exon 6 was flanked by loxP sites. (J:343548)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Zeb1 Mutation: 67 strains or lines available

References

• Original: J:343548 Martinez-Campanario MC, et al., Atherosclerotic plaque development in mice is enhanced by myeloid ZEB1 downregulation. Nat Commun. 2023 Dec 14;14(1):8316
• All: 2 reference(s)