Pax1dt^em1Rmh
Endonuclease-mediated Allele Detail

Summary

• Symbol: Pax1dt^em1Rmh
• Name: paired box 1 divergent transcript; endonuclease-mediated mutation 1, Richard M Harland
• MGI ID: MGI:7565345
• Synonyms: deltaPEAT
• Gene: Pax1dt Location: Chr2:147203461-147204713 bp, - strand Genetic Position: Chr2, 72.63 cM
• Alliance: Pax1dt^em1Rmh page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: CRISPR/Cas9 genome editing technology was used to generate a deletion of the entire transcribed unit. Whole mount in situ hybridization confirmed the absence of detectable signal in E9 homozygous mutant embryos. (J:239387)

Expression

In Mice Carrying this Mutation:

1 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Pax1dt Mutation: 0 strains or lines available

References

• Original: J:239387 Stafford DA, et al., Deletion of the sclerotome-enriched lncRNA PEAT augments ribosomal protein expression. Proc Natl Acad Sci U S A. 2017 Jan 03;114(1):101-106
• All: 1 reference(s)