Tg(Ccl19-tTA,-tdTomato)687Biat
Transgene Detail

Summary

• Symbol: Tg(Ccl19-tTA,-tdTomato)687Biat
• Name: transgene insertion 687, Biomodels Austria
• MGI ID: MGI:7564576
• Synonyms: Ccl19-tTA.v2
• Transgene: Tg(Ccl19-tTA,-tdTomato)687Biat Location: unknown
• Alliance: Tg(Ccl19-tTA,-tdTomato)687Biat page

Transgene origin

• Strain of Origin: C57BL/6N

Transgene description

• Transgene Type: Transgenic (Reporter, Transactivator)
• Mutation: Insertion
• Tg(Ccl19-tTA,-tdTomato)687Biat expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Ccl19 (MGI:1346316)

• Mutation details: The bacterial artificial chromosome (BAC) RPCI446D10 inserted with tetracycline transactivator gene (tTA) is downstream of Ccl19 promoter. Following with tTA gene locus, internal ribosomal entry site (IRES) with downstream tdTomato gene and polyadenylation signal were integrated into the BAC construct. (J:289764)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:289764 Chauveau A, et al., Visualization of T Cell Migration in the Spleen Reveals a Network of Perivascular Pathways that Guide Entry into T Zones. Immunity. 2020 May 19;52(5):794-807.e7
• All: 1 reference(s)