Tg(Itgax-LY75)#Mnz
Transgene Detail

Summary

• Symbol: Tg(Itgax-LY75)#Mnz
• Name: transgene insertion, Michel C Nussenzweig
• MGI ID: MGI:7562166
• Synonyms: CD11c-hDEC205, LY75-tg
• Transgene: Tg(Itgax-LY75)#Mnz Location: unknown
• Alliance: Tg(Itgax-LY75)#Mnz page

Transgene origin

• Strain of Origin: C57BL/6

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(Itgax-LY75)#Mnz expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  LY75 (4065)

  Ly75	(MGI:106662)

• Tg(Itgax-LY75)#Mnz expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Itgax (MGI:96609)

• Mutation details: Expression of the human lymphocyte antigen 75 cDNA (GenBank AY682091) is driven by the mouse integrin alpha X (CD11c) promoter (GenBank DQ658851). (J:117206)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:117206 Dudziak D, et al., Differential antigen processing by dendritic cell subsets in vivo. Science. 2007 Jan 5;315(5808):107-11
• All: 3 reference(s)