Ctla4^em1Anu
Endonuclease-mediated Allele Detail

Summary

• Symbol: Ctla4^em1Anu
• Name: cytotoxic T-lymphocyte-associated protein 4; endonuclease-mediated mutation 1, Australian National University
• MGI ID: MGI:7560636
• Gene: Ctla4 Location: Chr1:60948184-60954991 bp, + strand Genetic Position: Chr1, 30.58 cM, cytoband C
• Alliance: Ctla4^em1Anu page

Mutation origin

• Strain of Origin: C57BL/6NCrl

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: CRISPR-targeting generated a deletion from the T encoding M134 in exon 2, which translates into the ligand binding site and dimerization domain, and finishes before C211 in exon 4 or the cytoplasmic tail. . (J:276824)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ctla4 Mutation: 27 strains or lines available

References

• Original: J:276824 The Australian Phenomics Facility at The Australian National University, Information obtained from the Australian Phenomics Facility at The Australian National University. MGI Direct Data Submission. 2019
• All: 1 reference(s)