Serping1^tm1Dgen
Targeted Allele Detail

Summary

• Symbol: Serping1^tm1Dgen
• Name: serine (or cysteine) peptidase inhibitor, clade G, member 1; targeted mutation 1, Deltagen
• MGI ID: MGI:7548864
• Synonyms: C1inh^-
• Gene: Serping1 Location: Chr2:84595704-84605748 bp, - strand Genetic Position: Chr2, 49.45 cM
• Alliance: Serping1^tm1Dgen page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:342527
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• A lacZ-neomycin cassette was inserted in the 4th exon. (J:342527)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Serping1 Mutation: 30 strains or lines available

References

• Original: J:342527 Bupp S, et al., A novel murine in vivo model for acute hereditary angioedema attacks. Sci Rep. 2021 Aug 5;11(1):15924
• All: 1 reference(s)