Pgc^em1Hcz
Endonuclease-mediated Allele Detail

Summary

• Symbol: Pgc^em1Hcz
• Name: progastricsin (pepsinogen C); endonuclease-mediated mutation 1, Hua-Chuan Zheng
• MGI ID: MGI:7543060
• Gene: Pgc Location: Chr17:48037767-48045403 bp, + strand Genetic Position: Chr17, 23.98 cM, cytoband C
• Alliance: Pgc^em1Hcz page

Mutation origin

• Strain of Origin: Not Applicable

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Not Specified
• CRISPR-targeting of exon 2 and 3 merged parts of the exons and generated a null allele. (J:338079)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Pgc Mutation: 19 strains or lines available

References

• Original: J:338079 E Y, et al., The relationship between pepsinogen C and gastric carcinogenesis: a transgene and population study. BMC Cancer. 2023 Jun 8;23(1):520
• All: 1 reference(s)