Tmem117^em1Cya
Endonuclease-mediated Allele Detail

Summary

• Symbol: Tmem117^em1Cya
• Name: transmembrane protein 117; endonuclease-mediated mutation 1, Cyagen Biotechnology
• MGI ID: MGI:7541210
• Synonyms: TMEM117^flox
• Gene: Tmem117 Location: Chr15:94527113-94993979 bp, + strand Genetic Position: Chr15, 48.65 cM
• Alliance: Tmem117^em1Cya page

Mutation origin

• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready, No functional change)
• Mutation: Insertion
• Exon 3 was flanked by loxP sites via CRISPR/Cas9 technology. (J:341551)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Tmem117 Mutation: 37 strains or lines available

References

• Original: J:341551 Yang Y, et al., Transmembrane protein 117 knockdown protects against angiotensin-II-induced cardiac hypertrophy. Hypertens Res. 2023 Oct;46(10):2326-2339
• All: 1 reference(s)