Ncoa4^em1Cya
Endonuclease-mediated Allele Detail

Summary

• Symbol: Ncoa4^em1Cya
• Name: nuclear receptor coactivator 4; endonuclease-mediated mutation 1, Cyagen Biosciences
• MGI ID: MGI:7530944
• Synonyms: Ncoa4^fl
• Gene: Ncoa4 Location: Chr14:31881884-31901210 bp, + strand Genetic Position: Chr14, 19.4 cM, cytoband B
• Alliance: Ncoa4^em1Cya page

Mutation origin

• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready)
• Mutation: Insertion
• Exons 2-6 were flanked by loxP sites via CRISPR/Cas9 technology. (J:340760)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Ncoa4 Mutation: 76 strains or lines available

References

• Original: J:340760 Dai Y, et al., Mycobacterium tuberculosis hijacks host TRIM21- and NCOA4-dependent ferritinophagy to enhance intracellular growth. J Clin Invest. 2023 Apr 17;133(8)
• All: 1 reference(s)