Platr4^em1Bwu
Endonuclease-mediated Allele Detail

Summary

• Symbol: Platr4^em1Bwu
• Name: pluripotency associated transcript 4; endonuclease-mediated mutation 1, Baojian Wu
• MGI ID: MGI:7526546
• Gene: Platr4 Location: Chr3:41442116-41447634 bp, - strand Genetic Position: Chr3, 19.85 cM
• Alliance: Platr4^em1Bwu page

Mutation origin

• Strain of Origin: Not Specified

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR/Cas9 genome editing technology was used to generate a deletion of exons 1 and 2. (J:340221)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Platr4 Mutation: 0 strains or lines available

References

• Original: J:340221 Lin Y, et al., Oscillating lncRNA Platr4 regulates NLRP3 inflammasome to ameliorate nonalcoholic steatohepatitis in mice. Theranostics. 2021;11(1):426-444
• All: 1 reference(s)