Pcdha^tm25.1Tyag
Targeted Allele Detail

Summary

• Symbol: Pcdha^tm25.1Tyag
• Name: protocadherin alpha cluster; targeted mutation 25.1, Takeshi Yagi
• MGI ID: MGI:7523180
• Synonyms: Pcdha^SBC2deltaNeo
• Gene: Pcdha Location: unknown Genetic Position: Chr18, Syntenic

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:259649
• Parent Cell Line: TT2 (ES Cell)
• Strain of Origin: (C57BL/6NCrlj x CBA/JNCrlj)F1

Mutation description

• Allele Type: Targeted (Not Specified)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The targeting construct inserted a loxP and FRT flanked neomycin resistance cassette upstream of the variable region and constant 2 region (VCR2). Cre-mediated recombination removed the selection cassette. (J:259649)
• Inheritance: Not Specified

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Pcdha Mutation: 52 strains or lines available

References

• Original: J:259649 Katori S, et al., Protocadherin-alphaC2 is required for diffuse projections of serotonergic axons. Sci Rep. 2017 Nov 21;7(1):15908
• All: 1 reference(s)