Pcdha^tm24Tyag
Targeted Allele Detail

Summary

• Symbol: Pcdha^tm24Tyag
• Name: protocadherin alpha cluster; targeted mutation 24, Takeshi Yagi
• MGI ID: MGI:7522334
• Synonyms: Pcdha^deltaCR2
• Gene: Pcdha Location: unknown Genetic Position: Chr18, Syntenic

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:259627
• Parent Cell Line: TT2 (ES Cell)
• Strain of Origin: (C57BL/6NCrlj x CBA/JNCrlj)F1

Mutation description

• Allele Type: Targeted (Not Specified)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Germ line, cre-mediated trans-allelic recombination between Pcdha^tm1Tyag and Pcdha^tm5Tyag results in the deletion of CR2. (J:259627)
• Inheritance: Not Specified

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Pcdha Mutation: 52 strains or lines available

References

• Original: J:259627 Hasegawa S, et al., Constitutively expressed Protocadherin-alpha regulates the coalescence and elimination of homotypic olfactory axons through its cytoplasmic region. Front Mol Neurosci. 2012;5:97
• All: 1 reference(s)