Lrp12^em1(IMPC)Bay
Endonuclease-mediated Allele Detail

Summary

• Symbol: Lrp12^em1(IMPC)Bay
• Name: low density lipoprotein-related protein 12; endonuclease-mediated mutation 1, Baylor College of Medicine
• MGI ID: MGI:7510088
• Gene: Lrp12 Location: Chr15:39733985-39807390 bp, - strand Genetic Position: Chr15, 15.59 cM
• Alliance: Lrp12^em1(IMPC)Bay page
• IMPC: Lrp12 gene page

Mutation origin

• Strain of Origin: C57BL/6N
• Project Collection: IMPC

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: This allele was generated at Baylor College of Medicine using Cas9 and guides with spacer sequences AGACTATACACTACGCTGTG and GAAATGTAGGACGATTGATT that targeted exon(s) ENSMUSE00000125405.4. This resulted in deletion(s) of 9 bp (location: Chr15:39744007-39744015; GRCm39), 860 bp (location: Chr15:39743134-39743993; GRCm39). This description was generated automatically. Additional molecular information including FASTA sequence support for this allele can be found here: (IMPC Gene page) and viewed in a genome context here: (IMPC Genome Browser). (J:384794)

• Inheritance: Not Specified

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Lrp12 Mutation: 35 strains or lines available

References

• Original: J:265051 MGI and IMPC, MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC). Database Release. 2018-2023
• All: 3 reference(s)