Tg(Lck-Cdkn2a)1Mtkn
Transgene Detail

Summary

• Symbol: Tg(Lck-Cdkn2a)1Mtkn
• Name: transgene insertion 1, Masamoto Kanno
• MGI ID: MGI:7507549
• Synonyms: Tg(Lck-p19Arf)1
• Transgene: Tg(Lck-Cdkn2a)1Mtkn Location: unknown
• Alliance: Tg(Lck-Cdkn2a)1Mtkn page

Transgene origin

• Strain of Origin: C57BL/6

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(Lck-Cdkn2a)1Mtkn expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Cdkn2a (MGI:104738)

• Tg(Lck-Cdkn2a)1Mtkn expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Lck (MGI:96756)

• Mutation details: This transgene contains the mouse Lck genomic DNA, mouse p19Arf cDNA, human growth hormone genomic DNA. Lines 1 and 2 were generated. (J:132215)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:132215 Miyazaki M, et al., Thymocyte proliferation induced by pre-T cell receptor signaling is maintained through polycomb gene product Bmi-1-mediated Cdkn2a repression. Immunity. 2008 Feb;28(2):231-45
• All: 1 reference(s)