Tg(Pcp2-Src*Y535F)9Moka
Transgene Detail

Summary

• Symbol: Tg(Pcp2-Src*Y535F)9Moka
• Name: transgene insertion 9, Masato Okada
• MGI ID: MGI:7507075
• Synonyms: Tg(L7-nSrcY535F)9Okd
• Transgene: Tg(Pcp2-Src*Y535F)9Moka Location: unknown
• Alliance: Tg(Pcp2-Src*Y535F)9Moka page

Transgene origin

• Strain of Origin: (C57BL/6 x DBA)F1

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(Pcp2-Src*Y535F)9Moka expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Src (MGI:98397)

• Tg(Pcp2-Src*Y535F)9Moka expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Pcp2 (MGI:97508)

• Mutation details: The transgene contains the mouse promoter driving expression of the mouse gene with the mutation responsible for the amino acid substitution tyrosine with phenylalanine at position 535 (Y535F). (J:119931)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:119931 Kotani T, et al., Constitutive activation of neuronal Src causes aberrant dendritic morphogenesis in mouse cerebellar Purkinje cells. Neurosci Res. 2007 Feb;57(2):210-9
• All: 1 reference(s)