Tg(ApoE-Vkorc1l1)73Mf
Transgene Detail

Summary

• Symbol: Tg(ApoE-Vkorc1l1)73Mf
• Name: transgene insertion 73, Mathieu Ferron
• MGI ID: MGI:7495947
• Synonyms: Tg(ApoE-Vkorc1l1)73Maf
• Transgene: Tg(ApoE-Vkorc1l1)73Mf Location: unknown
• Alliance: Tg(ApoE-Vkorc1l1)73Mf page

Transgene origin

• Strain of Origin: (C3H/HeN C57BL/6J)F2

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(ApoE-Vkorc1l1)73Mf expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Vkorc1l1 (MGI:1916818)	3XFLAG-tagged version of mouse Vkorc1l1 cDNA

• Tg(ApoE-Vkorc1l1)73Mf expression driven by 1 gene
  Transgene expression driven by:
  

  Organism

  Driver Gene

  Homolog in Mouse

  Note

  human

  APOE (348)

  Apoe	(MGI:88057)

• Mutation details: Transgenic mice express a 3XFLAG-tagged version of mouse Vkorc1l1 cDNA under the control of a liver-specific human APOE promoter and regulatory sequences. (J:262230)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:262230 Lacombe J, et al., VKOR paralog VKORC1L1 supports vitamin K-dependent protein carboxylation in vivo. JCI Insight. 2018 Jan 11;3(1)
• All: 2 reference(s)