Pabir1em1.1Yhua
Endonuclease-mediated Allele Detail
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Symbol: |
Pabir1em1.1Yhua |
Name: |
PP2A A alpha (PPP2R1A) and B55A (PPP2R2A) interacting phosphatase regulator 1; endonuclease-mediated mutation 1.1, Ying Huang |
MGI ID: |
MGI:7494133 |
Synonyms: |
Fam122aflox |
Gene: |
Pabir1 Location: Chr19:24453866-24454720 bp, - strand Genetic Position: Chr19, 19.53 cM, cytoband C1
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Alliance: |
Pabir1em1.1Yhua page
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Strain of Origin: |
Not Specified
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Allele Type: |
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Endonuclease-mediated (Conditional ready) |
Mutation: |
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Insertion
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Mutation details: An artificial intron containing one loxP site was inserted into the middle of the single exon along with an FRT-flanked neomycin selection cassette to form two separated parts and a second loxP site was inserted into the 3-UTR region of the gene via CRISPR/Cas9 technology. The neomycin selection cassette was removed via flp-mediated recombination.
(J:337217, J:337007)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Pabir1 Mutation: |
5 strains or lines available
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Original: |
J:337217 Liu MH, et al., FAM122A is required for hematopoietic stem cell function. Leukemia. 2021 Jul;35(7):2130-2134 |
All: |
2 reference(s) |
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