Agbl4^tm1.2Ics
Targeted Allele Detail

Summary

• Symbol: Agbl4^tm1.2Ics
• Name: ATP/GTP binding protein-like 4; targeted mutation 1.2, Mouse Clinical Institute
• MGI ID: MGI:7494072
• Synonyms: Ccp6 KO
• Gene: Agbl4 Location: Chr4:110254858-111514707 bp, + strand Genetic Position: Chr4, 51.43 cM, cytoband C7
• Alliance: Agbl4^tm1.2Ics page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:267916
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129S2/SvPas

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: LoxP sites flank exon 7. An frt-flanked neomycin-resistance cassette was removed via Flp-mediated recombination, and Cre-mediated recombination removed exon 7. (J:267916)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Agbl4 Mutation: 47 strains or lines available

References

• Original: J:267916 Magiera MM, et al., Excessive tubulin polyglutamylation causes neurodegeneration and perturbs neuronal transport. EMBO J. 2018 Dec 3;37(23)
• All: 2 reference(s)