Del(19Fads1-Fads2)1Tkato
Endonuclease-mediated Allele Detail

Summary

• Symbol: Del(19Fads1-Fads2)1Tkato
• Name: deletion, Chr 19, Tadafumi Kato 1
• MGI ID: MGI:7490194
• Synonyms: Fads1/Fads2^em1.1Tkato
• Gene: Del(19Fads1-Fads2)1Tkato Location: unknown Genetic Position: Chr19, Syntenic

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intergenic deletion
• Del(19Fads1-Fads2)1Tkato involves 3 genes/genome features (Fads2, Gm50359, Fads1) View all
• Mutation details: CRISPR-targeting created a floxed segment using Fads1^em1Tkato and Fads2^em1Tkato. Recombinase removed the floxed segment. (J:336597)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Del(19Fads1-Fads2)1Tkato Mutation: 0 strains or lines available

References

• Original: J:336597 Yamamoto H, et al., GWAS-identified bipolar disorder risk allele in the FADS1/2 gene region links mood episodes and unsaturated fatty acid metabolism in mutant mice. Mol Psychiatry. 2023
• All: 1 reference(s)