Leprem2(cre/ERT2)Smoc
Endonuclease-mediated Allele Detail
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Symbol: |
Leprem2(cre/ERT2)Smoc |
Name: |
leptin receptor; endonuclease-mediated mutation 2, Shanghai Model Organisms Center |
MGI ID: |
MGI:7489534 |
Synonyms: |
LeprB-CreER, Lepr-CreER |
Gene: |
Lepr Location: Chr4:101574601-101672549 bp, + strand Genetic Position: Chr4, 46.96 cM
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Alliance: |
Leprem2(cre/ERT2)Smoc page
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Strain of Origin: |
Not Specified
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Allele Type: |
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Endonuclease-mediated (Inducible, Recombinase) |
Inducer: |
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tamoxifen |
Mutation: |
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Insertion
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Leprem2(cre/ERT2)Smoc expression driven by
1 gene
Knock-in expression driven by:
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Mutation details: IRES-iCreERT2 construct was inserted after exon 19 stop codon of Lepr gene. No molecular details are provided.
(J:327115)
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Activity: |
Tissue activity of this recombinase allele
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Driver:
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Lepr
(mouse)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Lepr Mutation: |
121 strains or lines available
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Original: |
J:327115 Liu Y, et al., Hedgehog signaling reprograms hair follicle niche fibroblasts to a hyper-activated state. Dev Cell. 2022 Jul 25;57(14):1758-1775.e7 |
All: |
1 reference(s) |
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