Rpl3l^em1Kei
Endonuclease-mediated Allele Detail

Summary

• Symbol: Rpl3l^em1Kei
• Name: ribosomal protein L3-like; endonuclease-mediated mutation 1, Keiichi I Nakayama
• MGI ID: MGI:7471435
• Gene: Rpl3l Location: Chr17:24946800-24955117 bp, + strand Genetic Position: Chr17, 12.52 cM, cytoband A3.3
• Alliance: Rpl3l^em1Kei page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR/Cas9 technology was used to delete exon 2. (J:335523)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Rpl3l Mutation: 27 strains or lines available

References

• Original: J:335523 Shiraishi C, et al., RPL3L-containing ribosomes determine translation elongation dynamics required for cardiac function. Nat Commun. 2023 Apr 20;14(1):2131
• All: 1 reference(s)