Tnfrsf12a^tm2Biib
Targeted Allele Detail

Summary

• Symbol: Tnfrsf12a^tm2Biib
• Name: tumor necrosis factor receptor superfamily, member 12a; targeted mutation 2, Biogen Idec
• MGI ID: MGI:7470776
• Synonyms: Fn14^fl, Tnfrsf12a^tm1Mcro
• Gene: Tnfrsf12a Location: Chr17:23894419-23896423 bp, - strand Genetic Position: Chr17, 11.99 cM
• Alliance: Tnfrsf12a^tm2Biib page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:335397
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Exons 2-4 were flanked by loxP sites. (J:335397)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Tnfrsf12a Mutation: 11 strains or lines available

References

• Original: J:335397 Gupta RK, et al., TWEAK functions with TNF and IL-17 on keratinocytes and is a potential target for psoriasis therapy. Sci Immunol. 2021 Nov 19;6(65):eabi8823
• All: 4 reference(s)