Dnd1^tm1.2Ysa
Targeted Allele Detail

Summary

• Symbol: Dnd1^tm1.2Ysa
• Name: DND microRNA-mediated repression inhibitor 1; targeted mutation 1.2, Yumiko Saga
• MGI ID: MGI:7469612
• Synonyms: Dnd1^delta
• Gene: Dnd1 Location: Chr18:36896724-36899267 bp, - strand Genetic Position: Chr18, 19.46 cM
• Alliance: Dnd1^tm1.2Ysa page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:288127
• Parent Cell Line: TT2 (ES Cell)
• Strain of Origin: (C57BL/6NCrlj x CBA/JNCrlj)F1

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: LoxP sites and an frt-flanked neomycin selection cassette were inserted to flank exons 2 and 3. FLP- and Cre-mediated recombination in the germline resulted in the deletion of the neomycin selection cassette and loxP-flanked sequences. (J:288127)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Dnd1 Mutation: 15 strains or lines available

References

• Original: J:288127 Imai A, et al., Mouse dead end1 acts with Nanos2 and Nanos3 to regulate testicular teratoma incidence. PLoS One. 2020;15(4):e0232047
• All: 1 reference(s)