Tal1^em1Ckc
Endonuclease-mediated Allele Detail

Summary

• Symbol: Tal1^em1Ckc
• Name: T cell acute lymphocytic leukemia 1; endonuclease-mediated mutation 1, Chin-Kai Chuang
• MGI ID: MGI:7466175
• Gene: Tal1 Location: Chr4:114913623-114928952 bp, + strand Genetic Position: Chr4, 52.73 cM
• Alliance: Tal1^em1Ckc page

Mutation origin

• Strain of Origin: FVB

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR-targeting of exon 4 deleted 118 bp resulting in an out of frame mutation. (J:334839)
• Inheritance: Not Specified

Expression

In Mice Carrying this Mutation:

23 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Tal1 Mutation: 33 strains or lines available

References

• Original: J:334839 Chuang CK, et al., The Role of SCL Isoforms in Embryonic Hematopoiesis. Int J Mol Sci. 2023 Mar 29;24(7)
• All: 1 reference(s)