Hhip^tm1.1Tipe
Targeted Allele Detail

Summary

• Symbol: Hhip^tm1.1Tipe
• Name: Hedgehog-interacting protein; targeted mutation 1.1, Tien Peng
• MGI ID: MGI:7464884
• Synonyms: Hhip^flox
• Gene: Hhip Location: Chr8:80692480-80784635 bp, - strand Genetic Position: Chr8, 37.95 cM, cytoband C3
• Alliance: Hhip^tm1.1Tipe page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:334907
• Parent Cell Line: Other (see notes) (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, Not Specified)
• Mutation: Insertion
• The targeting construct floxed exon 2. Recombination removed the selection cassette. (J:334907)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Hhip Mutation: 44 strains or lines available

Notes

ES cell = HF4 (129S/SvEv x C57BL/6)

References

• Original: J:334907 Wang C, et al., Dysregulated lung stroma drives emphysema exacerbation by potentiating resident lymphocytes to suppress an epithelial stem cell reservoir. Immunity. 2023 Mar 14;56(3):576-591.e10
• All: 1 reference(s)