Sucnr1^tm1.1Lixi
Targeted Allele Detail

Summary

• Symbol: Sucnr1^tm1.1Lixi
• Name: succinate receptor 1; targeted mutation 1.1, Xin Li
• MGI ID: MGI:7447090
• Gene: Sucnr1 Location: Chr3:59989290-59994987 bp, + strand Genetic Position: Chr3, 29.17 cM, cytoband D
• Alliance: Sucnr1^tm1.1Lixi page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:334149
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: TurboKnockout gene targeting strategy by Cyagen and Taconic was used to generated a floxed allele. No further information was provided. Cre-mediated recombination removed the floxed region generating a knock-out allele. (J:334149)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Sucnr1 Mutation: 27 strains or lines available

References

• Original: J:334149 Guo Y, et al., Targeting the succinate receptor effectively inhibits periodontitis. Cell Rep. 2022 Sep 20;40(12):111389
• All: 1 reference(s)