Dapl1^em1Isy
Endonuclease-mediated Allele Detail

Summary

• Symbol: Dapl1^em1Isy
• Name: death associated protein-like 1; endonuclease-mediated mutation 1, Yuji Ishii
• MGI ID: MGI:7442678
• Gene: Dapl1 Location: Chr2:59314997-59335364 bp, + strand Genetic Position: Chr2, 33.81 cM, cytoband C3
• Alliance: Dapl1^em1Isy page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: CRISPR-cas9 mediated recombination using guide RNAs created a 2.3 Kbp deletion spanning exons 2 and 3. (J:313784)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Dapl1 Mutation: 11 strains or lines available

References

• Original: J:313784 Chen HB, et al., DAPL1 is a novel regulator of testosterone production in Leydig cells of mouse testis. Sci Rep. 2021 Sep 17;11(1):18532
• All: 1 reference(s)