Slc7a3^tm1.1Ckq
Targeted Allele Detail

Summary

• Symbol: Slc7a3^tm1.1Ckq
• Name: solute carrier family 7 (cationic amino acid transporter, y+ system), member 3; targeted mutation 1.1, Cheng-Kui Qu
• MGI ID: MGI:7442636
• Synonyms: Slc7a3^f
• Gene: Slc7a3 Location: ChrX:100122816-100129626 bp, - strand Genetic Position: ChrX, 43.72 cM
• Alliance: Slc7a3^tm1.1Ckq page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:332221
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: (C57BL/6J x CBA/J)F2
• Project Collection: Lexicon

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: The targeting construct flanked exons 4 through 9, inserting an FRT-flanked neomycin resistance cassette into intron 3. Flp-mediated recombination removed the selection cassette. (J:332221)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Slc7a3 Mutation: 14 strains or lines available

References

• Original: J:332221 Yan Y, et al., Extracellular arginine is required but the arginine transporter CAT3 (Slc7a3) is dispensable for mouse normal and malignant hematopoiesis. Sci Rep. 2022 Dec 17;12(1):21832
• All: 1 reference(s)