Mettl14^em1Qys
Endonuclease-mediated Allele Detail

Summary

• Symbol: Mettl14^em1Qys
• Name: methyltransferase 14, N6-adenosine-methyltransferase subunit; endonuclease-mediated mutation 1, Qing-Yuan Sun
• MGI ID: MGI:7437746
• Gene: Mettl14 Location: Chr3:123161944-123179639 bp, - strand Genetic Position: Chr3, 53.96 cM
• Alliance: Mettl14^em1Qys page

Mutation origin

• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR-targeting deleted exon 2. (J:283320)

Expression

In Mice Carrying this Mutation:

3 assay results 1 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Mettl14 Mutation: 37 strains or lines available

References

• Original: J:283320 Meng TG, et al., Mettl14 is required for mouse postimplantation development by facilitating epiblast maturation. FASEB J. 2019 Jan;33(1):1179-1187
• All: 1 reference(s)