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Celsr1em1Ddev
Endonuclease-mediated Allele Detail
Summary
Symbol: Celsr1em1Ddev
Name: cadherin, EGF LAG seven-pass G-type receptor 1; endonuclease-mediated mutation 1, Danelle Devenport
MGI ID: MGI:7434998
Gene: Celsr1  Location: Chr15:85783130-85918404 bp, - strand  Genetic Position: Chr15, 40.42 cM
Alliance: Celsr1em1Ddev page
Mutation
origin
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Endonuclease-mediated (Null/knockout)
Mutation:    Intragenic deletion
 
Mutation detailsCRISPR/Cas9 technology generated an 81 bp deletion that includes the translation start site and the first 17 codons of the 29 amino acid sequence. (J:333055)
Expression
In Mice Carrying this Mutation: 12 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Celsr1 Mutation:  143 strains or lines available
References
Original:  J:333055 Basta LP, et al., Celsr1 and Celsr2 exhibit distinct adhesive interactions and contributions to planar cell polarity. Front Cell Dev Biol. 2022;10:1064907
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/14/2024
MGI 6.23
The Jackson Laboratory