Gcm2^{em2(Foxn1)Tbo}
Endonuclease-mediated Allele Detail

Summary

• Symbol: Gcm2^{em2(Foxn1)Tbo}
• Name: glial cells missing homolog 2; endonuclease-mediated mutation 2, Thomas Boehm
• MGI ID: MGI:7431264
• Gene: Gcm2 Location: Chr13:41254903-41264511 bp, - strand Genetic Position: Chr13, 20.31 cM
• Alliance: Gcm2^{em2(Foxn1)Tbo} page

Mutation origin

• Strain of Origin: FVB/N

Mutation description

• Allele Type: Endonuclease-mediated (Inserted expressed sequence)
• Mutations: Insertion, Intragenic deletion
• Gcm2^{em2(Foxn1)Tbo} expresses 1 gene
  Knock-in expresses:
  

  Organism	Expressed Gene	Note
  mouse	Foxn1 (MGI:102949)

• Mutation details: CRISPR-targeting replaced the coding sequence with the mouse coding sequence and floxed neomycin resistance cassette. (J:327225)
• Inheritance: Not Specified

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gcm2 Mutation: 34 strains or lines available

References

• Original: J:327225 Nagakubo D, et al., Limits to in vivo fate changes of epithelia in thymus and parathyroid by ectopic expression of transcription factors Gcm2 and Foxn1. Sci Rep. 2022 Aug 8;12(1):13554
• All: 1 reference(s)