Gria2^em1Ics
Endonuclease-mediated Allele Detail

Summary

• Symbol: Gria2^em1Ics
• Name: glutamate receptor, ionotropic, AMPA2 (alpha 2); endonuclease-mediated mutation 1, Mouse Clinical Institute
• MGI ID: MGI:7413970
• Synonyms: AP-GluA2 KI, Gria2^{em1(AP-TEV)Ics}
• Gene: Gria2 Location: Chr3:80588757-80710142 bp, - strand Genetic Position: Chr3, 35.5 cM
• Alliance: Gria2^em1Ics page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Epitope tag)
• Mutation: Insertion
• CRISPR-targeting inserted a biotin acceptor peptide (AP) tag on the extracellular N-terminus. (J:330791)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gria2 Mutation: 78 strains or lines available

References

• Original: J:330791 Getz AM, et al., High-resolution imaging and manipulation of endogenous AMPA receptor surface mobility during synaptic plasticity and learning. Sci Adv. 2022 Jul 29;8(30):eabm5298
• All: 1 reference(s)