Piezo1^em1Macki
Endonuclease-mediated Allele Detail

Summary

• Symbol: Piezo1^em1Macki
• Name: piezo-type mechanosensitive ion channel component 1; endonuclease-mediated mutation 1, Roderick MacKinnon
• MGI ID: MGI:7345564
• Synonyms: PIEZO1-HA
• Gene: Piezo1 Location: Chr8:123208437-123278068 bp, - strand Genetic Position: Chr8, 71.31 cM
• Alliance: Piezo1^em1Macki page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Epitope tag)
• Mutation: Insertion
• Mutation details: CRISPR/cas9 methodologies are used to introduce a hemagglutinin (HA) tag just after amino acid 893 in exon 20. (J:101977)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Piezo1 Mutation: 88 strains or lines available

References

• Original: J:101977 The Jackson Laboratory, Information obtained from The Jackson Laboratory, Bar Harbor, ME. Unpublished. 2005-2017
• All: 2 reference(s)